A sticky problem that is holding back the therapeutic use of stem cells bioengineered from adult tissue (induced pluripotent stem cells or iPS cells), is the risk that any residual undifferentiated ones will remain and form tumors after transplant into the patient. So while iPS stem cell therapy may be effective, as long as this problem remains, it is unsafe...
Source: http://www.medicalnewstoday.com/articles/250795.php
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